‘Getting the dose right’ – A blog by Dr Jan Hansel
 
                        
                        
                        
                                                        Author: Dr Jan Hansel
                            
                        
                                                As part of World Antimicrobial Awareness Week (18 to 24 November 2023), Dr Jan Hansel discusses the importance of therapeutic drug monitoring in limiting the development of antimicrobial resistance (AMR) and the new Manchester BRC-funded TDM-TIME study which he is leading.
                        
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                        Disturbed sleep may partially explain Long COVID breathlessness, find researchers
 
                        
                        
                        
                                                A major UK study has discovered that the disturbed sleep patterns in patients hospitalised with COVID-19 was likely to be a driver of breathlessness.
                        
                        Continue reading  full article: Disturbed sleep may partially explain Long COVID breathlessness, find researchers
                    
                     
                
                                        
                    
                                        
                                        
                    
                        
                        
                        
                        Malfunctioning immune cell behaviour could be drug target in Long Covid
 
                        
                        
                        
                                                Greater Manchester researchers have shown for the first time that malfunctioning behaviour of a type of immune cell is linked to specific symptoms of Long COVID.
                        
                        Continue reading  full article: Malfunctioning immune cell behaviour could be drug target in Long Covid
                    
                     
                
                                        
                    
                                        
                                        
                    
                        
                        
                        
                        Manchester BRC researcher receives prestigious international early career research honour
 
                        
                        
                        
                                                A researcher at Manchester BRC has won a celebrated international prize, in recognition for his work in respiratory (breathing) research.
                        
                        Continue reading  full article: Manchester BRC researcher receives prestigious international early career research honour
                    
                     
                
                                        
                    
                                        
                                        
                    
                        
                        
                        
                        ‘World-first’ graphene-based test could rapidly detect patients’ need for antibiotic treatment
 
                        
                        
                        
                                                Research into a new generation of a graphene-based diagnostic test – which could identify patients who need antibiotics in minutes, instead of hours – will be delivered in Manchester.
                        
                        Continue reading  full article: ‘World-first’ graphene-based test could rapidly detect patients’ need for antibiotic treatment
                    
                     
                
                                        
                    
                                        
                                        
                    
                        
                        
                        
                        Manchester BRC researchers receive prestigious national appointments
 
                        
                        
                        
                                                Three researchers from Manchester Biomedical Research Centre (BRC) have been appointed Senior Investigators by the National Institute for Health Research (NIHR).
                        
                        Continue reading  full article: Manchester BRC researchers receive prestigious national appointments
                    
                     
                
                                        
                    
                                        
                                        
                    
                        
                        
                        
                        Global trials show drug eases symptoms of chronic cough
 
                        
                        
                        
                                                The results of the world’s first Phase 3 trials, of a new drug Gefapixant, show that it can ease the often distressing symptoms of chronic cough, with minimal side effects.
                        
                        Continue reading  full article: Global trials show drug eases symptoms of chronic cough
                    
                     
                
                                        
                    
                                        
                                        
                    
                        
                        
                        
                        COVID-19 study finds continuous positive airway pressure (CPAP) reduces need for invasive ventilation in hospitalised patients
 
                        
                        
                        
                                                Professor Paul Dark, Non-fungal Infections Programme Lead, is one of the authors of the paper “Effect of noninvasive respiratory strategies on intubation or mortality among patients with acute hypoxemic respiratory failure and COVID-19,” recently published in  JAMA.
                        
                        Continue reading  full article: COVID-19 study finds continuous positive airway pressure (CPAP) reduces need for invasive ventilation in hospitalised patients