NIHR | Manchester Biomedical Research Centre
Our Research:

Respiratory Medicine

Respiratory ill-health presents a huge unmet need with significant morbidity, mortality and health inequalities linked to high levels of deprivation. Reducing mortality and morbidity of respiratory disease is our overarching aim.

In Manchester, social deprivation negatively impacts on respiratory health.

Our aim is to develop novel biomarker-led diagnostic and prognostic strategies, facilitating precision therapeutic approaches, to improve outcomes for patients. This has been shaped in collaboration with our respiratory patients through VOCAL, Asthma and Lung UK, and Let’s Talk About Cough.

Our Respiratory Medicine Theme contains four programmes:

  • Precision diagnostics and therapeutics in airways disease
  • Understanding and improving airway symptoms and function
  • Exacerbation mechanisms and diagnosis
  • Precision therapy in respiratory infections/Exacerbations


Our theme capitalises on our international leadership in COPD, respiratory symptoms, infection and asthma and is based within one of the largest clinical respiratory departments in the UK – at Manchester University NHS Foundation Trust’s Wythenshawe Hospital.