We work closely with NIHR Biomedical Research Centres and other parts of NIHR infrastructure:
- NIHR Manchester Clinical Research Facility
Jacky Smith NIHR Manchester CRF Director is also our Improving Respiratory Symptom’s Lead and Alex Horsley, Medical Director, Manchester Clinical Research Facility at Wythenshawe Hospital,
- NIHR Clinical Research Network
Paul Dark is the NIHR Clinical Research Network National Specialty Lead for Critical Care. NIHR Clinical Research Network Greater Manchester: Leads for Critical Care (Tim Felton) and Children (Clare Murray)
- NIHR Translational Research Partnership (Respiratory)
The NIHR Respiratory Translational Research brings together internationally recognised investigators in the UK’s leading centres of excellence to carry out experimental and early phase research with industry, charities and other funders.
- NIHR Senior Investigators
Our Respiratory theme joins researchers with charities, industry and key infrastructure support to combat the burden of respiratory diseases.
In the UK, our theme is part of the MRC funded COPD-MAP and founding partner of the UK Early COPD cohort funded by the British Lung Foundation and industry. We are part of the recently established European project CADSET – Chronic Airway Diseases Stratification by Endotypes. We are world-leading in clinical trials in COPD and work with almost all pharmaceutical companies with an interest in COPD.
Our fungal disease research is undertaken in the UK and across the world, currently in Uganda, Nigeria and Indonesia. We partner with diagnostic and antifungal development companies to deliver a better understanding of fungal diseases, optimise diagnostics and therapies, and identify resistance. A major theme is chronic pulmonary aspergillosis after TB, on which we have worked with the World Health Organisation to develop a definition of disease for low resource settings. Fungal diagnostic provision is part of the solution to AMR, to reduce antibacterial empiricism.