Musculoskeletal disorders, such as rheumatoid arthritis, psoriatic arthritis, lupus, osteoarthritis and juvenile idiopathic arthritis, account for around 20% of all GP consultations in the UK.
The economic impact of these disorders is significant, not only due to the related disability they cause but also due to the cost of treatment or surgery.
The musculoskeletal theme is split into four programmes, with a large focus on using biomarkers to help predict outcomes and personalisation of treatment.
We have a strong track record of musculoskeletal research having had one of only three musculoskeletal NIHR Biomedical Research Units (BRU) previously, which undertook translational clinical research in musculoskeletal disorders and formed the basis of the musculoskeletal theme within the BRC. We are also recognised as a European Alliance of Associations for Rheumatology (EULAR) centre of excellence for research and have two Versus Arthritis Centres of Excellence.
Centre for Genetics & Genomics Versus Arthritis, based at The University of Manchester, aims to understand the role of genetic factors in determining whether particular people are at risk of developing inflammatory arthritis and what happens when they do.
Centre for Epidemiology Versus Arthritis is based at The University of Manchester. Their research is focused on investigating the cause and progression of musculoskeletal conditions in specific populations; the response to treatment and development of side-effects and the impact of arthritis on work/life. There is a particular focus on inflammatory arthritis (such as rheumatoid arthritis and psoriatic arthritis) and osteoarthritis.