NIHR | Manchester Biomedical Research Centre
Our Research: Hearing Health

Developing genetic and genomic solutions

How can genomics help us learn more about hearing health?

Precision medicine helps us to find out more about the genomic landscape of hearing and listening difficulties. Utilising our infrastructure, informatics and biomarker platforms expertise, we will revolutionise our knowledge of hearing health to aid diagnosis and management, and to test strategies to improve outcomes across all ages.

We plan to:

  • Use genome sequencing in new-born screening to improve diagnosis
  • Discover genetic variants of vestibular schwannomas, benign brain tumours, in Neurofibromatosis type 2 patients to develop therapeutic targets, linking in with the Cancer Prevention and Early Detection Theme
  • Evaluate point-of-care testing to provide rapid diagnosis of ototoxic gentamicin-related hearing loss