Did you know that 1 in 20 cancers in the UK are linked to being overweight? How will our research empower people to protect themselves against cancer, in the context of a rising obesity epidemic?
Over the next 20 years the increase in obesity is expected to result in around 670,000 new cases of cancer. By 2035, 72% of UK adults are predicted to be overweight or obese (up from 62% in 2014), with many being from low income households.
Through our research we are:
- Identifying those individuals most at risk by better characterising the type and timing of excess weight associated with obesity related cancer.
- Evaluating the effectiveness of different approaches to support weight loss and weight gain prevention programmes, and how these can be used in different populations.
The research in this programme will be supported by the Informatics & Data Sciences crossing-cutting theme.
Progress to date
- Co-designed a weight gain prevention app for high risk young women to reduce breast cancer risk, based on research on why women gain weight and acceptable weight maintenance programmes.
- Findings from a large UK cohort with new-onset type 2 diabetes (T2D), elevated BMI either prior to or at T2D diagnosis was associated with higher risk of obesity-related cancers in women, more in never-smokers, but not in men reinforcing the need for improved weight management in people with T2D.
- Collaboration with Southampton BRC within the Family History Lifestyle Study, testing remotely delivered lifestyle programmes amongst women in the high risk breast cancer clinic
- Weight loss surgery for obese women prevents womb cancer.
- Prevent obesity induced Endometrial Cancer.
- Determine when is the optimal time to intervene in a person’s life in terms of preventing weight gain/addressing weight loss.
- Refine the cancer prevention message for obesity related cancers to identify and target those specifically at risk due to ethnic, genetic, epigenetic or other characteristics.
- Deliver low-cost interventions to support high-risk populations to achieve lifestyle change for weight loss and the prevention of weight gain.